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Likewise, chewing gum [25] and sham feeding [26] as non-invasive cephalic stimulation, were sufficient to up-regulate vagal tone and then normalized meal-induced antral dysmotility in FD patients or reduced time to flatus and time to passage of bowel motion in POI patients

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The specific time of day to take tesofensine would depend on the instructions provided by the prescribing physician or healthcare professional